Wellington Oyibo
FBMS
Med. Micro & Para
Prof.
Malaria and NTDs
Dr. Oyegbola
Science
Physics
S/L
Optics
Dr. Taiwo Adubi
Science
Zoology
Lect II
NTD
Dr. O.Akande
FBMS
Biochem
Ass. Prof
NTDs
Dr. M.J Fasona
Soc Sc
Geography
Ass Prof.
GIS/Remote Sensing
Dr. Ifeoma Udenze
Clinical Science
Clinical Pathology
S/Lect
Pathology
Chris Makwe
Clinical Sciences
O&G
S/Lect.
TD/Female Genital Schistosomiasis
Dr. Chimere Agomo
FBMS
Med. Lab. Sci
S/L
Malaria & NTDs
Dr. Lekan Oyefera
Soc Science
Sociology
Ass Prof.
Culture/Sociology of development
Anunobi
FBMS
Morbid & Anatomic
Prof.
Bladder carcinoma of Schistosomiasis
Dr. Chimere Agomo
FBMS
Med. Lab. Sci
S/L
Malaria & NTDs
Dr. Victor Odumuyiwa
Science
Comp Sc
Ass. Prof.
Big Data
Rose Anorlu
Clinical Sciences
O&G
Prof
NTD/Female Genital Schistosomiasis
RESOURCES AVAILABLE FOR IN THE CENTRE
GENERAL FACILITIES/INFRASTRUCTURE AVAILABLE
1. RENOVATED ROOMS WITH STANDARD INTERNET NETWORK FOR CONNECTIVITY
2. ALTERNATE POWER GENERATING SET (10KVA)
3. 70 BINOCULAR MICROSCOPES
4. -86 oC FREEZER (3)
5. -40 Oc FREEZERS (10)
6. Preparation room
7. ELISA READER
8. MALARIA SPECIMEN BANK CONTAINING PANELS HIGHLY CHARACTERIZED PANELS
9. CERTIFIED MICROSCOPISTS
ELISA-BASED DIAGNOSIS FOR MALARIA ANTIGENS, ANTIBODIES ETC
We have capacity to elucidate and measure malaria parasite antigens, antibodies (imminoglobulins), cytokines, chemokines and other immune responses. Furthermore, we have capacity to measure several fever biomarkers along side inflammatory markers in febrile patients.
MOLECULAR DIAGNOSIS FOR MALARIA
Molecular diagnosis of malaria is more sensitive than light microscopy and rapid diagnostic tests. Apart from species identification, molecular techniques are used for identification of single nucleotide polymorphisms used for strain and clone differentiation among malaria parasites. This is important in a) drug efficacy trials where differentiation of recrudescence from re-infection is very important in determining the antimalarial drug efficacy; b) population studies on malaria parasite diversity in the different ecological zones of Nigeria; and c) prediction of antimalarial drug resistance by the prevalence of markers of antimalarial drug resistance.
The ANDI Centre has the capacity in terms of personnel and equipment to undertake all aspects of the above mentioned applications of molecular diagnosis of malaria.
Personnel
The Centre has highly trained personnel in molecular techniques such as
· Nucleic acid isolation and purification
· Malaria species (P. falciparum, P. malariae, P. vivax, P. ovale and P. knowlesi) identification by nested PCR and restriction fragment length polymorphisms (RFLP)
· Sequence analysis and alignment for detection of single nucleotide polymorphisms
· Differentiation of recrudescence from re-infection in patients treated for falciparum malaria by PCR-RFLP